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A New Look At Irritable Bowel Disease and Viruses: The Core Human "Phageome"
An illustration of the core protein clusters (PCs; groups of similar genes) found in the photic and aphotic zones of the ocean. This new study applies a similar approach using phage genomes instead of genes. Source |
Ongoing research has continued to implicate the microbiome in a variety of human diseases. We often hear about this in the context of bacterial communities. Certain bacterial communities appear to be associated with health, and disrupting these communities seems to be associated with disease. To better understand these bacterial communities, we sometimes group the shared members together as the "core bacterial community" that is associated with health or disease. In some ways these core bacteria are considered important to the system because they are found in every instance of health or disease. But what about the core phages (bacterial viruses) of these communities? A few weeks ago Manrique et al published a study that began addressing this question.
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